Structure of PDB 8tlk Chain B

Receptor sequence
>8tlkB (length=101) Species: 9606 (Homo sapiens) [Search protein sequence]
VTLPHIIRPVEEITEEELENVCSNSREKIYNRSLGSTCHQCRQKTIDTKT
NCRNPDCWGVRGQFCGPCLRNRYGEEVRDALLDPNWHCPPCRGICNCSFC
R
3D structure
PDB8tlk The ICF syndrome protein CDCA7 harbors a unique DNA-binding domain that recognizes a CpG dyad in the context of a non-B DNA.
ChainB
Resolution2.99 Å
3D
structure
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Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna B V233 T234 L235 R258 R264 T269 R274 Q275 K276 W290 G291 V292 V1 T2 L3 R26 R32 T37 R42 Q43 K44 W58 G59 V60
BS02 ZN B C270 C273 C300 C38 C41 C68
BS03 ZN B H271 C329 C332 H39 C97 C100
BS04 ZN B C284 C289 C320 C323 C52 C57 C88 C91
External links
PDB RCSB:8tlk, PDBe:8tlk, PDBj:8tlk
PDBsum8tlk
PubMed38168392
UniProtQ9BWT1|CDCA7_HUMAN Cell division cycle-associated protein 7 (Gene Name=CDCA7)

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