Structure of PDB 8tlh Chain B

Receptor sequence
>8tlhB (length=104) Species: 10090 (Mus musculus) [Search protein sequence]
SMTLPHIIRPVEEVTEEEIRNICSNSREKIYNRSLGSTCHQCRQKTTDTK
TNCRNPDCWGIRGQFCGPCLRNRYGEEVKDALLDPNWHCPPCRGICNCSF
CRQR
3D structure
PDB8tlh The ICF syndrome protein CDCA7 harbors a unique DNA-binding domain that recognizes a CpG dyad in the context of a non-B DNA.
ChainB
Resolution1.94 Å
3D
structure
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Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna B S243 M244 T245 L246 S268 R269 R275 T280 R285 Q286 K287 W301 G302 I303 S1 M2 T3 L4 S26 R27 R33 T38 R43 Q44 K45 W59 G60 I61
BS02 ZN B C281 C284 C311 C39 C42 C69
BS03 ZN B H282 C338 C340 C343 H40 C96 C98 C101
BS04 ZN B C295 C300 C331 C334 C53 C58 C89 C92
External links
PDB RCSB:8tlh, PDBe:8tlh, PDBj:8tlh
PDBsum8tlh
PubMed38168392
UniProtQ9D0M2|CDCA7_MOUSE Cell division cycle-associated protein 7 (Gene Name=Cdca7)

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