Structure of PDB 8tfz Chain B

Receptor sequence
>8tfzB (length=177) Species: 70601 (Pyrococcus horikoshii OT3) [Search protein sequence]
SRFKVSKLMAYILAHSPWEFGLEPDEEGFVSIEELVNAVRKVYPWVTEEY
IREIVERDEKGRYEIRGNKIRARYGHSYPVILRHEEDKESKVLYHGTVRR
NLKGIMREGIKPGKRQYVHLSINYEDAYNTGMRHGEDVVVLIIDAECLRN
KGYKILKAGKKVRIVKHVPVDCISGIL
3D structure
PDB8tfz Structural basis for Tpt1-catalyzed 2'-PO 4 transfer from RNA and NADP(H) to NAD.
ChainB
Resolution2.06 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.1.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 NAD B Y74 H95 G96 T97 G104 I105 E108 I110 K111 R115 H119 L120 T130 R133 H134 V162 Y74 H95 G96 T97 G104 I105 E108 I110 K111 R115 H119 L120 T130 R133 H134 V162
Gene Ontology
Molecular Function
GO:0000215 tRNA 2'-phosphotransferase activity
GO:0003950 NAD+-protein poly-ADP-ribosyltransferase activity
GO:0016740 transferase activity
GO:0016772 transferase activity, transferring phosphorus-containing groups
Biological Process
GO:0006388 tRNA splicing, via endonucleolytic cleavage and ligation

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Molecular Function
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Biological Process
External links
PDB RCSB:8tfz, PDBe:8tfz, PDBj:8tfz
PDBsum8tfz
PubMed37883434
UniProtO57899|KPTA_PYRHO Probable RNA 2'-phosphotransferase (Gene Name=kptA)

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