Structure of PDB 8tfp Chain B

Receptor sequence

>8tfpB (length=215) Species: 9606 (Homo sapiens) [Search protein sequence]

QVQLQESGPGLVKPSGTLSLTCTVSGGFISSRNWWSWVRQPPGKGLEWIG
EVYHTGITNYNPSLKSRVTISVDKSKNQFSLKLSSVTAADTAVYYCAREV
VGPTTGYFDLWGRGTLVTIVSRRLPPSVFPLAPSGGTAALGCLVKDYFPE
PVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNV
NHKPSNTKVDKKVEP

3D structure

PDB

8tfp An Engineered Human-Antibody Fragment with Fentanyl Pan-Specificity That Reverses Carfentanil-Induced Respiratory Depression.

Chain

Resolution

1.78 Å

3D
structure

[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	84K	B	W34 E50 N58 E95 V97 G100B	W34 E51 N59 E99 V101 G106

External links

PDB	RCSB:8tfp, PDBe:8tfp, PDBj:8tfp
PDBsum	8tfp
PubMed	37534714

[Back to BioLiP]