Structure of PDB 8tee Chain B

Receptor sequence
>8teeB (length=429) Species: 10090 (Mus musculus) [Search protein sequence]
LDGIRMPDGCYADGTWELSVHVTDLNRDVTLRVTGEVHIGGVMLKLVEKL
DVKKDWSDHALWWEKKRTWLLKTHWTLDKCGIQADAKLQFTPQHKLLRLQ
LPNMKYVKVKVNFSDRVFKAVSDICKTFNIRHPEELSLLKKPRDPPGILA
VSQPVTSPEILAKMFKPQALLDKAKTNQGWLDSSRSLMEQDVKENEALLL
RFKYYSFFDLNPKYDAIRINQLYEQAKWALLLEEIECTEEEMMMFAALQY
HINKLSIMTSENHLTTDVNPECLVSPRYLKKYKSKQITARILEAHQNVAQ
MSLIEAKMRFIQAWQSLPEFGITHFIARFQGGKREELIGIAYNRLIRMDA
STGDAIKTWRFSNMKQWNVNWEIKMVTVEFADEVRLSFICTEVDCKVVHE
FIGGYIFLSTRAKDESLDEEMFYKLTSGW
3D structure
PDB8tee Acetyl-NPKY of integrin-beta 1 binds KINDLIN2 to control endothelial cell proliferation and junctional integrity.
ChainB
Resolution2.49 Å
3D
structure
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Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 peptide B M612 K613 Q614 W615 N616 V617 W619 T658 M364 K365 Q366 W367 N368 V369 W371 T410
External links
PDB RCSB:8tee, PDBe:8tee, PDBj:8tee
PDBsum8tee
PubMed38904068
UniProtQ8CIB5|FERM2_MOUSE Fermitin family homolog 2 (Gene Name=Fermt2)

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