Structure of PDB 8t6v Chain B

Receptor sequence
>8t6vB (length=516) Species: 9606 (Homo sapiens) [Search protein sequence]
DDPLQQTGQLFGGLVRDIRRRYPYYLSDITDAFSPQVLAAVIFIYFAALS
PAITFGGLLGEKTRNQMGVSELLISTAVQGILFALLGAQPLLVVGFSGPL
LVFEEAFFSFCETNGLEYIVGRVWIGFWLILLVVLVVAFEGSFLVRFISR
YTQEIFSFLISLIFIYETFSKLIKIFQDHPLQKTYNYNVLMVPKPQGPLP
NTALLSLVLMAGTFFFAMMLRKFKNSSYFPGKLRRVIGDFGVPISILIMV
LVDFFIQDTYTQKLSVPDGFKVSNSSARGWVIHPLGLRSEFPIWMMFASA
LPALLVFILIFLESQITTLIVSKPERKMVKGSGFHLDLLLVVGMGGVAAL
FGMPWLSATTVRSVTHANALTVMGKAQIQEVKEQRISGLLVAVLVGLSIL
MEPILSRIPLAVLFGIFLYMGVTSLSGIQLFDRILLLFKPPKYHPDVPYV
KRVKTWRMHLFTGIQIICLAVLWVVKSTPASLALPFVLILTVPLRRVLLP
LIFRNVELQCLDADDA
3D structure
PDB8t6v Substrate binding and inhibition of the anion exchanger 1 transporter.
ChainB
Resolution2.95 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 4DS B T422 G466 P467 I528 I531 F532 E535 K539 K851 L859 T54 G98 P99 I160 I163 F164 E167 K171 K476 L484
BS02 CLR B I442 W648 I74 W280
Gene Ontology
Molecular Function
GO:0005452 solute:inorganic anion antiporter activity
Biological Process
GO:0006820 monoatomic anion transport
Cellular Component
GO:0016020 membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8t6v, PDBe:8t6v, PDBj:8t6v
PDBsum8t6v
PubMed37679563
UniProtP02730|B3AT_HUMAN Band 3 anion transport protein (Gene Name=SLC4A1)

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