Structure of PDB 8szu Chain B

Receptor sequence
>8szuB (length=342) Species: 470 (Acinetobacter baumannii) [Search protein sequence]
KKIGYVWDTLYSWVDAANLSKRIQPITHHMNHPDTKRRFNELVMTSGQID
FLTPIKPYPATDADILRVHDKQLLDNAKNGGIEIAYLSAGGAIELTKKVI
SGELHTGYALVSPPGHHATKKDSMGFCIFNNTSIAAAYAKDILGLKRVAI
VDWDVHHGNGTQDIWWEDSSVLTISIHQNKCFPTNSGFINERGAGNGFGY
NLNIPLPPGSGNGAYIYAFEKVIVPALKKYEPELIIVGSGFDASILDPLS
RMMVSSEGFKKMASLILEVSNEINGGKCLFVQEGGYSPHYLPFCGLAVIE
ALTGMHTLDDPLIDMVGEMGGNELLPHEKKVVDECANLIADI
3D structure
PDB8szu Structure and Function of Kdac1, a Class II Deacetylase from the Multidrug-Resistant Pathogen Acinetobacter baumannii .
ChainB
Resolution1.75 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 X4U B H316 P338 L339 H289 P311 L312
BS02 X4U B L273 L339 M342 M346 L246 L312 M315 M319
BS03 X4U B A24 I31 H143 H144 G152 F153 D181 H183 F209 Y313 A16 I23 H116 H117 G125 F126 D154 H156 F182 Y286
BS04 ZN B D181 H183 D269 D154 H156 D242
Gene Ontology
Molecular Function
GO:0004407 histone deacetylase activity
GO:0046872 metal ion binding
Biological Process
GO:0000122 negative regulation of transcription by RNA polymerase II
GO:0006338 chromatin remodeling
Cellular Component
GO:0005737 cytoplasm

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Molecular Function
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Cellular Component
External links
PDB RCSB:8szu, PDBe:8szu, PDBj:8szu
PDBsum8szu
PubMed37624144
UniProtR8YPJ7

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