Structure of PDB 8sxy Chain B

Receptor sequence
>8sxyB (length=358) Species: 262724 (Thermus thermophilus HB27) [Search protein sequence]
MWVKILSVVGARPQFIKAAAVSRVLRASPGVREVLVHTGQHSQVFFEELE
IPDPDYHLGIGGGTHGQNTGRMLEAIEGVLLKEKPDWVLVYGDTDSTLAG
ALAAVKLHIPVAHVEAGLRSFNRRMPEEINRILTDHASDLLFAPTETAVQ
NLLREGIPENRIHLVGDVMYDAALHYGAKAERKSRILERLGLQAKGYVLA
TIHRAENTDDQERLRVILEALAEVHQEVPVVFPVHPRTRKRAEAFGLGSY
LEKVVALEPVGYLDMVMLEKNARLIVTDSGGVQKEAYFYRVPCVTVREET
EWVELLKAEWNYLAAPQNAKDLALTILHRMRTKGVEIDLYGDGRASQKIS
DFLRKVGI
3D structure
PDB8sxy Structural analysis of a bacterial UDP-sugar 2-epimerase reveals the active site architecture before and after catalysis.
ChainB
Resolution1.8 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 5.1.3.14: UDP-N-acetylglucosamine 2-epimerase (non-hydrolyzing).
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 MJ3 B R12 P13 Q14 I16 K17 G97 D98 E120 E132 H208 V265 Y267 M270 S284 G285 G286 E290 W307 R12 P13 Q14 I16 K17 G92 D93 E115 E127 H203 V260 Y262 M265 S279 G280 G281 E285 W302
Gene Ontology
Molecular Function
GO:0000166 nucleotide binding
GO:0003824 catalytic activity
GO:0008761 UDP-N-acetylglucosamine 2-epimerase activity
GO:0016853 isomerase activity

View graph for
Molecular Function
External links
PDB RCSB:8sxy, PDBe:8sxy, PDBj:8sxy
PDBsum8sxy
PubMed37660908
UniProtQ72KY0

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