Structure of PDB 8sxe Chain B

Receptor sequence
>8sxeB (length=361) Species: 287 (Pseudomonas aeruginosa) [Search protein sequence]
SAPLPLDELRTFAEVLDRVKAAYVEPVDDKTLLENAIKGMLSNLDPHSAY
LGPEDFAELQESTSGEFGGLGIEVGSEDGFIKVVSPIDDTPAARAGIQPG
DLIVQIDGKPTKGQSMTEAVDSMRGKAGSPITLTIVRDGGRPFDVELKRA
IIKVKSVKSQVLEPGYAYLRITQFQVNTGEEVVKALNQLRKDNKGRLKGL
VLDLRNNPGGVLQSAVEVADAFLTKGLIVYTKGRIANSELRFSADPADPS
DKVPLVVLINGGSAAAAEIVAGALQDQKRAILMGTDSFGKGSVQTVLPLN
NDRALKLTTALYYTPNGRSIQAQGIVPDIEVGRAKVRPQDSDYQLSQALS
LLKGLSVTRGN
3D structure
PDB8sxe P. aeruginosa CtpA protease adopts a novel activation mechanism to initiate the proteolytic process
ChainB
Resolution3.55 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide B I366 Y418 L426 G429 L430 T433 R434 I329 Y343 L351 G354 L355 T358 R359
Gene Ontology
Molecular Function
GO:0004175 endopeptidase activity
GO:0004252 serine-type endopeptidase activity
GO:0008236 serine-type peptidase activity
Biological Process
GO:0006508 proteolysis
GO:0007165 signal transduction
GO:0030254 protein secretion by the type III secretion system
GO:0042546 cell wall biogenesis
GO:0043163 cell envelope organization
Cellular Component
GO:0005886 plasma membrane
GO:0030288 outer membrane-bounded periplasmic space
GO:0030313 cell envelope
GO:0042597 periplasmic space

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8sxe, PDBe:8sxe, PDBj:8sxe
PDBsum8sxe
PubMed38467832
UniProtQ9HU50

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