Structure of PDB 8sms Chain B

Receptor sequence
>8smsB (length=405) Species: 83333 (Escherichia coli K-12) [Search protein sequence]
VSKRAVITGLGIVSSIGNNQQEVLASLREGRSGITFSQELKDSGMRSHVW
GNVKLDTTGLIDRKVVRFMSDASIYAFLSMEQAIADAGLSPEAYQNNPRV
GLIAGSGGGSPRFQVFGADAMRGPRGLKAVGPYVVTKAMASGVSACLATP
FKIHGVNYSISSACATSAHCIGNAVEQIQLGKQDIVFAGGGEELCWEMAC
EFDAMGALSTKYNDTPEKASRTYDAHRDGFVIAGGGGMVVVEELEHALAR
GAHIYAEIVGYGATSDGADMVAPSGEGAVRCMKMAMHGVDTPIDYLNSHG
TSTPVGDVKELAAIREVFGDKSPAISATKAMTGHSLGAAGVQEAIYSLLM
LEHGFIAPSINIEELDEQAAGLNIVTETTDRELTTVMSNSFGFGGTNATL
VMRKL
3D structure
PDB8sms Masked cerulenin enables a dual-site selective protein crosslink
ChainB
Resolution1.93 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.3.1.41: beta-ketoacyl-[acyl-carrier-protein] synthase I.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 G7U B G106 A162 C163 M197 F201 V270 H298 T302 G305 H333 F390 G391 F392 G107 A163 C164 M198 F202 V271 H299 T303 G306 H334 F391 G392 F393
Gene Ontology
Molecular Function
GO:0004315 3-oxoacyl-[acyl-carrier-protein] synthase activity
GO:0016746 acyltransferase activity
GO:0016747 acyltransferase activity, transferring groups other than amino-acyl groups
Biological Process
GO:0006633 fatty acid biosynthetic process
GO:0044281 small molecule metabolic process
GO:1903966 monounsaturated fatty acid biosynthetic process
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol

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Molecular Function
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Cellular Component
External links
PDB RCSB:8sms, PDBe:8sms, PDBj:8sms
PDBsum8sms
PubMed37829009
UniProtP0A953|FABB_ECOLI 3-oxoacyl-[acyl-carrier-protein] synthase 1 (Gene Name=fabB)

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