Structure of PDB 8sk1 Chain B

Receptor sequence
>8sk1B (length=160) Species: 1392 (Bacillus anthracis) [Search protein sequence]
MNNIAYIALGSNIGERYTYLTEAIQFLNKNPYIKVEDVSSVYETEPVGYT
DQSCFLNLVIKISTNLSPQELLKVTQKVENDLGRKREIRWGPRTIDLDIL
LYNQENIEAENLIVPHPRMFERAFVIVPLLEINQDIKQNISRSQVEEMKR
REGVTVWKQK
3D structure
PDB8sk1 Crystal structure of Bacillus anthracis HPPK in complex with bisubstrate inhibitor HP-73
ChainB
Resolution2.0 Å
3D
structure
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Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 H73 B E87 R89 W90 E87 R89 W90
BS02 H73 B T44 E45 V47 F55 N57 R93 D96 D98 I99 N111 L112 I113 H116 R122 F124 T44 E45 V47 F55 N57 R93 D96 D98 I99 N111 L112 I113 H116 R122 F124
Gene Ontology
Molecular Function
GO:0003848 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase activity
GO:0005524 ATP binding
GO:0016301 kinase activity
Biological Process
GO:0016310 phosphorylation
GO:0046654 tetrahydrofolate biosynthetic process
GO:0046656 folic acid biosynthetic process

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Molecular Function

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Biological Process
External links
PDB RCSB:8sk1, PDBe:8sk1, PDBj:8sk1
PDBsum8sk1
PubMed
UniProtA0A6L7HDR0

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