Structure of PDB 8sk0 Chain B

Receptor sequence
>8sk0B (length=330) Species: 47853 (Micromonospora carbonacea) [Search protein sequence]
LVPRGSVPRVFVAGGAGFIGSHYVRELVAGAYAGWQGCEVTVLDSLTYAG
NLANLAGVRDAVTFVRGDICDGRLLAEVLPGHDVVLNFAAETHVDRSIAD
SAEFLRTNVQGVQSLMQACLTAGVPTIVQVSTDEVYGSIEAGSWSEDAPL
APNSPYAAAKAGGDLIALAYARTYGLPVRITRCGNNYGPYQFPEKVIPLF
LTRLMDGRSVPLYGDGRNVRDWIHVADHCRGIQTVVERGASGEVYHIAGT
AELTNLELTQHLLDAVGGSWDAVERVPDRKGHDRRYSLSDAKLRALGYAP
RVPFADGLAETVAWYRANRHWWEPLRKQLD
3D structure
PDB8sk0 EvdS6 is a bifunctional decarboxylase from the everninomicin gene cluster.
ChainB
Resolution1.51 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 4.2.1.46: dTDP-glucose 4,6-dehydratase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 NAD B G11 F12 I13 D38 S39 L40 T41 G44 D62 I63 F82 A83 A84 T86 T101 V124 Y150 K154 G178 N180 G17 F18 I19 D44 S45 L46 T47 G50 D68 I69 F88 A89 A90 T92 T107 V130 Y156 K160 G184 N186
Gene Ontology
Molecular Function
GO:0000166 nucleotide binding
GO:0008460 dTDP-glucose 4,6-dehydratase activity
GO:0016829 lyase activity
Biological Process
GO:0009225 nucleotide-sugar metabolic process

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Molecular Function
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Biological Process
External links
PDB RCSB:8sk0, PDBe:8sk0, PDBj:8sk0
PDBsum8sk0
PubMed37286037
UniProtA0A1C5ADV9

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