Structure of PDB 8shh Chain B

Receptor sequence
>8shhB (length=324) Species: 47853 (Micromonospora carbonacea) [Search protein sequence]
VPRVFVAGGAGFIGSHYVRELVAGAYAGWQGCEVTVLDSLTYAGNLANLA
GVRDAVTFVRGDICDGRLLAEVLPGHDVVLNFAAETHVDRSIADSAEFLR
TNVQGVQSLMQACLTAGVPTIVQVSTDEVYGSIEAGSWSEDAPLAPNSPY
AAAKAGGDLIALAYARTYGLPVRITRCGNNYGPYQFPEKVIPLFLTRLMD
GRSVPLYGDGRNVRDWIHVADHCRGIQTVVERGASGEVYHIAGTAELTNL
ELTQHLLDAVGGSWDAVERVPDRKGHDRRYSLSDAKLRALGYAPRVPFAD
GLAETVAWYRANRHWWEPLRKQLD
3D structure
PDB8shh EvdS6 is a bifunctional decarboxylase from the everninomicin gene cluster.
ChainB
Resolution1.93 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number 4.2.1.46: dTDP-glucose 4,6-dehydratase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 NAD B G11 F12 I13 D38 S39 L40 T41 G44 D62 F82 A83 A84 T86 T101 V124 S125 Y150 K154 G178 N179 G11 F12 I13 D38 S39 L40 T41 G44 D62 F82 A83 A84 T86 T101 V124 S125 Y150 K154 G178 N179
Gene Ontology
Molecular Function
GO:0000166 nucleotide binding
GO:0008460 dTDP-glucose 4,6-dehydratase activity
GO:0016829 lyase activity
Biological Process
GO:0009225 nucleotide-sugar metabolic process

View graph for
Molecular Function
View graph for
Biological Process
External links
PDB RCSB:8shh, PDBe:8shh, PDBj:8shh
PDBsum8shh
PubMed37286037
UniProtA0A1C5ADV9

[Back to BioLiP]