Structure of PDB 8rzc Chain B

Receptor sequence
>8rzcB (length=116) Species: 2697049 (Severe acute respiratory syndrome coronavirus 2) [Search protein sequence]
CAFAVDAAKAYKDYLASGGQPITNCVKMLCTHTGTGQAITVTPEANMDQE
SFGGASCCLYCRCHIDHPNPKGFCDLKGKYVQIPTTCANDPVGFTLKNTV
CTVCGMWKGYGCSCDQ
3D structure
PDB8rzc Towards automated crystallographic structure refinement with phenix.refine.
ChainB
Resolution2.35 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.7.50: mRNA guanylyltransferase.
3.4.19.12: ubiquitinyl hydrolase 1.
3.4.22.-
3.4.22.69: SARS coronavirus main proteinase.
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 ZN B C117 C120 C128 C130 C101 C104 C112 C114
BS02 ZN B C74 C77 H83 C90 C58 C61 H67 C74
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0008270 zinc ion binding
Biological Process
GO:0019079 viral genome replication

View graph for
Molecular Function

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Biological Process
External links
PDB RCSB:8rzc, PDBe:8rzc, PDBj:8rzc
PDBsum8rzc
PubMed
UniProtP0DTC1|R1A_SARS2 Replicase polyprotein 1a

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