Structure of PDB 8ryk Chain B

Receptor sequence
>8rykB (length=153) Species: 9606 (Homo sapiens) [Search protein sequence]
APVRSLNCTLRDSQQKSLVMSGPYELKALHLQGQDMEQQVVFSMSFVQGE
ESNDKIPVALGLKEKNLYLSCVLKDDKPTLQLESVDPKNYPKKKMEKRFV
FNKIEINNKLEFESAQFPNWYISTSQAENMPVFLGGTKGGQDITDFTMQF
VSS
3D structure
PDB8ryk Ligandability Assessment of IL-1 beta by Integrated Hit Identification Approaches.
ChainB
Resolution1.8 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 peptide B D76 W120 G135 G136 T137 D76 W120 G135 G136 T137
BS02 peptide B V3 R4 S5 L6 N7 S43 L62 K63 Y68 P87 K88 Y90 P91 S153 V3 R4 S5 L6 N7 S43 L62 K63 Y68 P87 K88 Y90 P91 S153
External links
PDB RCSB:8ryk, PDBe:8ryk, PDBj:8ryk
PDBsum8ryk
PubMed38728572
UniProtP01584|IL1B_HUMAN Interleukin-1 beta (Gene Name=IL1B)

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