Structure of PDB 8rvb Chain B

Receptor sequence
>8rvbB (length=115) Species: 2697049 (Severe acute respiratory syndrome coronavirus 2) [Search protein sequence]
AFAVDAAKAYKDYLASGGQPITNCVKMLCTHTGTGQAITVTPEANMDQES
FGGASCCLYCRCHIDHPNPKGFCDLKGKYVQIPTTCANDPVGFTLKNTVC
TVCGMWKGYGCSCDQ
3D structure
PDB8rvb SARS-CoV-2 nsp16-nsp10 in complex with SAM derivative inhibitor 8
ChainB
Resolution1.95 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.7.50: mRNA guanylyltransferase.
3.4.19.12: ubiquitinyl hydrolase 1.
3.4.22.-
3.4.22.69: SARS coronavirus main proteinase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ZN B C74 C77 H83 C90 C57 C60 H66 C73
BS02 ZN B C117 C120 C128 C130 C100 C103 C111 C113
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0008270 zinc ion binding
Biological Process
GO:0019079 viral genome replication

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Molecular Function
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Biological Process
External links
PDB RCSB:8rvb, PDBe:8rvb, PDBj:8rvb
PDBsum8rvb
PubMed
UniProtP0DTC1|R1A_SARS2 Replicase polyprotein 1a

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