Structure of PDB 8rq9 Chain B

Receptor sequence
>8rq9B (length=120) Species: 9606 (Homo sapiens) [Search protein sequence]
DSQQHPAPEKSSKVSEQLKCCSGILKEMFAHAAYAWPFYKPVDVEALGLH
DYCDIIKHPMDMSTIKSKLEAREYRDAQEFGADVRLMFSNCYKYNPPDHE
VVAMARKLQDVFEMRFAKMP
3D structure
PDB8rq9 Design of a Cereblon construct for crystallographic and biophysical studies of protein degraders
ChainB
Resolution2.91 Å
3D
structure
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Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 A1H2F B A370 W374 F376 N433 V439 A32 W36 F38 N95 V101
External links
PDB RCSB:8rq9, PDBe:8rq9, PDBj:8rq9
PDBsum8rq9
PubMed
UniProtO60885|BRD4_HUMAN Bromodomain-containing protein 4 (Gene Name=BRD4)

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