Structure of PDB 8rnc Chain B

Receptor sequence

>8rncB (length=718) Species: 1601067 (Influenza B virus (B/Memphis/13/2003))

MNINPYFLFIDVPIQAAISTTFPYTGVPPYSTGTGYTIDTVIRTHEYSNK
GKQYISDVTGCTMVDPTNGPLPEDNEPSAYAQLDCVLEALDRMDEEHPGL
FQAASQNAMETLMVTTVDKLTQGRQTFDWTVCRNQPAATALNTTITSFRL
NDLNGADKGGLIPFCQDIIDSLDRPEMTFFSVKNIKKIKRIPMKVKDKIT
KVEYIKRALSLNTMTKDAERGKLKRRAIATAGIQIRGFVLVVENLAKNIC
ENLEQSGLPVGGNEKKAKLSNAVAKMLSNCPPGGISMTVTGDNTKWNECL
NPRIFLAMTERITRDSPIWFRDFCSIAPVLFSNKIARLGKGFMITSKTKR
LKAQIPCPDLFSIPLERYNEETRAKLKKLKPFFNEEGTASLSPGMMMGMF
NMLSTVLGVAALGIKNIGNKEYLWDGLQSSDDFALFVNAKDEETCMEGIN
DFYRTCKLLGINMSKKKSYCNETGMFEFTSMFYRDGFVSNFAMELPSFGV
AGVNESADMAIGMTIIKNNMINNGMGPATAQTAIQLFIADYRYTYKCHRG
DSKVEGKRMKIIKELWENTKGRDGLLVADGGPNIYNLRNLHIPEIVLKYN
LMDPEYKGRLLHPQNPFVGHLSIEGIKEADKKMDYDAVSGTHSWRTKRNE
EQCYAKCCNLFEACFNSASYRKPVGQHSMLEAMAHRLRMDARLDYESGRM
SKDDFEKAMAHLGEIGYI

3D structure

• PDB: 8rnc Structures of influenza A and B replication complexes give insight into avian to human host adaptation and reveal a role of ANP32 as an electrostatic chaperone for the apo-polymerase.
• Chain: B
• Resolution: 3.52 Å

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	peptide	B	K362 L364	K349 L351

External links

• PDB: RCSB:8rnc, PDBe:8rnc, PDBj:8rnc
• PDBsum: 8rnc
• PubMed: 39160148
• UniProt: Q5V8Y6