Structure of PDB 8rh9 Chain B

Receptor sequence

>8rh9B (length=333) Species: 9606 (Homo sapiens) [Search protein sequence]

KSEQLLRIDDHDFSMRPGFGGPAIPVGVDVQVESLDSISEVDMDFTMTLY
LRHYWKDERLSFPSTNNLSMTFDGRLVKKIWVPDMFFVHSKRSFIHDTTT
DNVMLRVQPDGKVLYSLRVTVTAMCNMDFSRFPLDTQTCSLEIESYAYTE
DDLMLYWKKGNDSLKTDERISLSQFLIQEFHTTTKLAFYSSTGWYNRLYI
NFTLRRHIFFFLLQTYFPATLMVMLSWVSFWIDRRAVPARVPLGITTVLT
MSTIITGVNASMPRVSYIKAVDIYLWVSFVFVFLSVLEYAAVNYLTTVQE
RKEQDTHAIDKYSRIIFPAAYILFNLIYWSIFS

3D structure

PDB

8rh9 Divergent mechanisms of steroid inhibition in the human rho1 GABAA receptor

Chain

Resolution

3.21 Å

3D
structure

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Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	A8W	B	P311 L322	P238 L249

External links

PDB	RCSB:8rh9, PDBe:8rh9, PDBj:8rh9
PDBsum	8rh9
PubMed
UniProt	P24046\|GBRR1_HUMAN Gamma-aminobutyric acid receptor subunit rho-1 (Gene Name=GABRR1)

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