Structure of PDB 8rgs Chain B

Receptor sequence
>8rgsB (length=362) Species: 1916 (Streptomyces lividans) [Search protein sequence]
GSAVPFHGAHQAGIATPVQDRLHFAAFDVTTEDRAAFVALLKEWTAAARR
LTAGHAVGEGAYGGLPEAPPDDTGEALGLKPSRLTLTIGFGPSLFTRFGL
ADLRPEALADLPKFPGDNLDRARSGGDLCVQACADDPQVAVHAIRNLARI
GFGKVVVRWSQLGFGKTSSTTPDKQTPRNLLGFKDGTRNIAGTEKDRLDR
FVWAAEKDGTPWMTGGSYLVARRIRMHIETWDRASLQEQEDVFGRDKGEG
APVGKAKERDEPFLKAMKPDAHVRLAHPDSNGGATLLRRGYSFTDGTDGL
GRLDAGLFFLAYQRDIRTGFVPVQRNLATALNEFIQHVGSAVFAVPPGVR
DADDWWGSTLFG
3D structure
PDB8rgs Efficient in situ screening of and data collection from microcrystals in crystallisation plates
ChainB
Resolution1.79 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 1.11.1.-
4.98.1.1: protoporphyrin ferrochelatase.
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 HEM B N233 K238 G240 T241 R242 M280 F297 H326 V327 A330 H331 R342 L361 F363 F374 Q378 L381 L386 N179 K184 G186 T187 R188 M226 F243 H272 V273 A276 H277 R288 L307 F309 F320 Q324 L327 L331
Gene Ontology
Molecular Function
GO:0004601 peroxidase activity
GO:0020037 heme binding
Biological Process
GO:0033212 iron import into cell

View graph for
Molecular Function

View graph for
Biological Process
External links
PDB RCSB:8rgs, PDBe:8rgs, PDBj:8rgs
PDBsum8rgs
PubMed38488731
UniProtA0A7U9DT46

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