Structure of PDB 8rcf Chain B

Receptor sequence

>8rcfB (length=311) Species: 9606 (Homo sapiens) [Search protein sequence]

GPQPISRLEQCGINANDVKKLEEAGFHTVEAVAYAPKKELINIKGISEAK
ADKILAEAAKLVPMGFTTATEFHQRRSEIIQITTGSKELDKLLQGGIETG
SITEMFGEFRTGKTQICHTLAVTCQLPIDRGGGEGKAMYIDTEGTFRPER
LLAVAERYGLSGSDVLDNVAYARAFNTDHQTQLLYQASAMMVESRYALLI
VDSATALYRTDYSGRGELSARQMHLARFLRMLLRLADEFGVAVVITNQVV
AQVDPKKPIGGNIIAHASTTRLYLRKGRGETRICKIYDSPCLPEAEAMFA
INADGVGDAKD

3D structure

PDB

8rcf RAD51 protects abasic sites to prevent replication fork breakage.

Chain

Resolution

3.4 Å

3D
structure

[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)
BS01	dna	B	R229 R241 Q242 M243 V270 A271 V273 G288 G289 N290	R209 R221 Q222 M223 V250 A251 V253 G260 G261 N262
BS02	dna	B	R235 D274	R215 D254
BS03	ATP	B	R130 T131 G132 K133 T134 Q135 R170 I329 N330	R110 T111 G112 K113 T114 Q115 R150 I301 N302
BS04	CA	B	A293 H294 S296 D316	A265 H266 S268 D288
BS05	ATP	B	H294 S317 P318 C319 L320 P321	H266 S289 P290 C291 L292 P293

External links

PDB	RCSB:8rcf, PDBe:8rcf, PDBj:8rcf
PDBsum	8rcf
PubMed	39178838
UniProt	Q06609\|RAD51_HUMAN DNA repair protein RAD51 homolog 1 (Gene Name=RAD51)

[Back to BioLiP]