Structure of PDB 8r5n Chain B

Receptor sequence
>8r5nB (length=165) Species: 9606 (Homo sapiens) [Search protein sequence]
GNVARVVVWEWLNEHSRWRPYTATVCHHIENVLKEDARGSVVLGQVDAQL
VPYIIDLQSMHQFRQDTGTMRPVRRNFYDPSSAPGKGIVWEWENDGGAWT
AYDMDICITIQNAYEKQHPWLDLSSLGFCYLIYFNSMSQMNRQTRRRRRL
RRRLDLAYPLTVGSI
3D structure
PDB8r5n A ligand discovery toolbox for the WWE domain family of human E3 ligases
ChainB
Resolution1.812 Å
3D
structure
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Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ATP B K135 H137 K116 H118
BS02 ATP B W30 E33 Y72 Q81 R83 T88 R90 W11 E14 Y53 Q62 R64 T69 R71
External links
PDB RCSB:8r5n, PDBe:8r5n, PDBj:8r5n
PDBsum8r5n
PubMed39048679
UniProtQ86Y01|DTX1_HUMAN E3 ubiquitin-protein ligase DTX1 (Gene Name=DTX1)

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