Structure of PDB 8r2o Chain B

Receptor sequence
>8r2oB (length=425) Species: 9606,1327989 [Search protein sequence]
IEEGKLVIWINGDKGYNGLAEVGKKFEKDTGIKVTVEHPDKLEEKFPQVA
ATGDGPDIIFWAHDRFGGYAQSGLLAEITPDKAFQDKLYPFTWDAVRYNG
KLIAYPIAVEALSLIYNKDLLPNPPKTWEEIPALDKELKAKGKSALMFNL
QEPYFTWPLIAADGGYAFKYENGKYDIKDVGVDNAGAKAGLTFLVDLIKN
KHMNADTDYSIAEAAFNKGETAMTINGPWAWSNIDTSKVNYGVTVLPTFK
GQPSKPFVGVLSAGINAASPNKELAKEFLENYLLTDEGLEAVNKDKPLGA
VALKSYEEELAKDPRIAATMENAQKGEIMPNIPQMSAFWYAVRTAVINAA
SGRQTVDAALAAAQTNAAAGSENLYFQGMATLEKLMKAFESLKSFQQQQQ
QQQQQQQQQQQQPPPPPPPPPPPQL
3D structure
PDB8r2o Post-translational modifications in the first 17 amino acids of huntingtin influence self-association and interaction with membranes
ChainB
Resolution3.23 Å
3D
structure
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Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 GLC B K15 W62 E111 Y155 K14 W61 E110 Y154
BS02 GLC B W62 D65 R66 E153 P154 Y155 W340 W61 D64 R65 E152 P153 Y154 W339
External links
PDB RCSB:8r2o, PDBe:8r2o, PDBj:8r2o
PDBsum8r2o
PubMed
UniProtA0A4P1LXE0;
P42858|HD_HUMAN Huntingtin (Gene Name=HTT)

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