Structure of PDB 8r2h Chain B

Receptor sequence
>8r2hB (length=701) Species: 5833 (Plasmodium falciparum) [Search protein sequence]
DIGKYFKQINTFINIDEYKTIYGDEIYKEIYELYVERNIPEYYERKYFSE
DIKKSVLFDIDKYNDVEFEKAIKEEFINNGVYINNIDNTYYKKENILIMK
KILHYFPLLKLINNPSDLKKLKKQYLPLLAHELKIFLFFIVNITGGHFSS
VLSSLEIQLLLLYIFNQPYDNVIYDIGHQAYVHKILTGRKLLFLSLRNKK
GISGFLNIFESIYDKFGAGHSSTSLSAIQGYYEAEWQVKNKEVDKVHIAI
IGDGGLTGGMALEALNYISFLNSKILIIYNDNGQVSLPTNAVSISGNRPI
GSISDHLHYFVNNIFENLNYDYIGVVNGNNTEELFKVLNNIKENKLKRAT
VLHVRTKKSNKYEDMFSKETFTDIYTNEMLKYLKKDRNIIFLSPAMLGGS
GLVKISERYPNNVYDVGIAEQHSVTFAAAMAMNKKLKIQLCIYSTFLQRA
YDQIIHDLNLQNIPLKVIIGRSGLVGEDGATHQGIYDLSYLGTLNNAYII
SPSNQVDLKRALRFAYLDKDHSVYIRIPRMNILSDKYMKGYLNIMDDDNF
IKSFIGKSRIIKMTKKKKVCIFNMGSMLFNVINAIKEIEKEQYISHNYSF
SIVDMIFLNPLDKNMIDHVIKQNKHQYLITYEDNTIGGFSTHFNNYLIEN
NYITKHNLYVHNIYLSNEPIEHASFKDQQEVVKMDKCSLVNRIKNYLKNN
P
3D structure
PDB8r2h Cryo-EM structure of 1-deoxy-D-xylulose 5-phosphate synthase (DXPS) from Plasmodium falciparum
ChainB
Resolution2.42 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.2.1.7: 1-deoxy-D-xylulose-5-phosphate synthase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 MG B D628 N657 Q659 D253 N282 Q284
BS02 TPP B H489 S532 D628 G629 G630 N657 L662 A854 I877 F905 H178 S221 D253 G254 G255 N282 L287 A395 I418 F446
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