Structure of PDB 8qzx Chain B

Receptor sequence
>8qzxB (length=333) Species: 5722 (Trichomonas vaginalis) [Search protein sequence]
TPLVKGYVPDDNGKFDFDKMLEQMKYCGFQATNLGLAIDQINEMLHYDYE
KLFGLGGGVEGVKYKPRACKIFLGITSNLISSGMRDYIRFLVKHALVDVV
VCTAGGIEEDFIKCLAPTHMGEFFHDGHDLRKRGLNRIGNLIVPNKNYCL
FEDWIMPILDKCLEEQNTQGTKWTPSKLIHRLGLEINNEDSVWYWAAKNN
IPVYSPALTDGSIGDMIYFHSYNNPGLVLDLVEDIRDMNNEPLWATKTGC
IILGGGVVKHHIMNANLYRNGADFVVYVNTAHDFDGSDSGARPDEAVSWG
AISLEAKPVKVYAEVTLVLPLLVAGSFSKFLAE
3D structure
PDB8qzx Structural characterization of the (deoxy)hypusination in Trichomonas vaginalis questions the bifunctionality of deoxyhypusine synthase.
ChainB
Resolution3.01 Å
3D
structure
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Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 NAD B D315 S317 D318 S319 D285 S287 D288 S289
BS02 NAD B S107 N108 T133 G135 I168 D240 G284 G285 N309 V345 S77 N78 T103 G105 I138 D210 G254 G255 N279 V315
Gene Ontology
Molecular Function
GO:0034038 deoxyhypusine synthase activity
Biological Process
GO:0008612 peptidyl-lysine modification to peptidyl-hypusine
Cellular Component
GO:0005737 cytoplasm

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Molecular Function

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Biological Process

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Cellular Component
External links
PDB RCSB:8qzx, PDBe:8qzx, PDBj:8qzx
PDBsum8qzx
PubMed38923395
UniProtF1AQF9

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