Structure of PDB 8qze Chain B

Receptor sequence
>8qzeB (length=454) Species: 1404 (Priestia megaterium) [Search protein sequence]
IKEMPQPKTFGELKNLPLLNTDKPVQALMKIADELGEIFKFEAPGRVTRY
LSSQRLVKEACDESRFDKNLSQALKFVRDFAGDGLVTSWTHEKNWKKARN
ILLPSLSQQAMKGYHAMMVDIAVQLVQKWERLNSDEHIEVPEDVTRLTLD
TIGLCGFNYRFNSFYRDQPHPFITSMVRALDEAMNKLQRANPDDPAYDEN
KRQFQEDIKVMNDLVDKIIADRKASGEQSDDLLTHMLHGKDPETGEPLDD
ENIRYQIITFLIAGHETTSGLLTFALYFLVKNPHVLQKAAEEAARVLVDP
VPSYKQVKQLKYVGMVLNEALRLWPTFPAFSLYAKEDTVLGGEYPLEKGD
ELMVLIPQLHRDKTIWGDDVEEFRPERFENPSAIPQHAFKPFGNGQRACI
GQQFALHEATLVLGMMLKHFDFEDHTNYELDIEETLTLKPEGFVIKAKSK
KIPL
3D structure
PDB8qze Revisiting strategies and their combinatorial effect for introducing peroxygenase activity in CYP102A1 (P450BM3)
ChainB
Resolution1.87 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 1.14.14.1: unspecific monooxygenase.
1.6.2.4: NADPH--hemoprotein reductase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 HEM B K69 L86 V87 W96 R100 F261 A264 G265 T268 F328 F331 P392 F393 R398 C400 I401 G402 A406 K68 L85 V86 W95 R99 F260 A263 G264 T267 F327 F330 P391 F392 R397 C399 I400 G401 A405
Gene Ontology
Molecular Function
GO:0004497 monooxygenase activity
GO:0005506 iron ion binding
GO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
GO:0020037 heme binding

View graph for
Molecular Function
External links
PDB RCSB:8qze, PDBe:8qze, PDBj:8qze
PDBsum8qze
PubMed
UniProtP14779|CPXB_PRIM2 Bifunctional cytochrome P450/NADPH--P450 reductase (Gene Name=cyp102A1)

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