Structure of PDB 8qz4 Chain B

Receptor sequence
>8qz4B (length=259) Species: 9606 (Homo sapiens) [Search protein sequence]
WKTVVAIFVVVVVYLVTGGLVFRALEQPFESSQKNTIALEKAEFLRDHVC
VSPQELETLIQHALDADNAGVSPIGNSSSSHWDLGSAFFFAGTVITTIGY
GNIAPSTEGGKIFCILYAIFGIPLFGFLLAGIGDQLGTIFGKSIARVEKV
FRKKQVSQTKIRVISTILFILAGCIVFVTIPAVIFKYIEGWTALESIYFV
VVTLTTVGFGDFVAGGNAYREWYKPLVWFWILVGLAYFAAVLSMIGDWLR
VLSKKTKEE
3D structure
PDB8qz4 Extracellular modulation of TREK-2 activity with nanobodies provides insight into the mechanisms of K2P channel regulation.
ChainB
Resolution3.2 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 Y01 B F188 L191 F195 F113 L116 F120
BS02 Y01 B V83 Y87 L330 S331 V10 Y14 L252 S253
BS03 Y01 B V251 F252 F260 L304 F307 V176 F177 F185 L226 F229
External links
PDB RCSB:8qz4, PDBe:8qz4, PDBj:8qz4
PDBsum8qz4
PubMed38755204
UniProtP57789|KCNKA_HUMAN Potassium channel subfamily K member 10 (Gene Name=KCNK10)

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