Structure of PDB 8qz2 Chain B

Receptor sequence
>8qz2B (length=246) Species: 9606 (Homo sapiens) [Search protein sequence]
KTVVAIFVVVVVYLVTGGLVFRALEQPFESSQKNTIALEKAEFLRDHVCV
SPQELETLIQHALDADNAGVSPIGQSSQQSSHWDLGSAFFFAGTVITTIG
YGNIAPSTEGGKIFCILYAIFGIPLFGFLLAGIGDQLGTIFGKSIARVEK
VFVSQTKIRVISTILFILAGCIVFVTIPAVIFKYIEGWTALESIYFVVVT
LTTVGFGDFVAGGNAGINYREWYKPLVWFWILVGLAYFAAVLSMIG
3D structure
PDB8qz2 Extracellular modulation of TREK-2 activity with nanobodies provides insight into the mechanisms of K2P channel regulation.
ChainB
Resolution3.5 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 K B G174 Y175 G176 G283 F284 G285 G100 Y101 G102 G205 F206 G207
BS02 K B I173 G174 Y175 V282 G283 F284 I99 G100 Y101 V204 G205 F206
BS03 K B T172 I173 G174 T281 V282 G283 T98 I99 G100 T203 V204 G205
BS04 K B T172 I173 T281 T98 I99 T203
External links
PDB RCSB:8qz2, PDBe:8qz2, PDBj:8qz2
PDBsum8qz2
PubMed38755204
UniProtP57789|KCNKA_HUMAN Potassium channel subfamily K member 10 (Gene Name=KCNK10)

[Back to BioLiP]