Structure of PDB 8qrs Chain B

Receptor sequence
>8qrsB (length=415) Species: 9606 (Homo sapiens) [Search protein sequence]
LRANLLVLLTVVAVVAGVALGLGVSGAGGALALGPERLSAFVFPGELLLR
LLRMIILPLVVCSLIGGAASLDPGALGRLGAWALLFFLVTTLLASALGVG
LALALQPGAASKEVLDSFLDLARNIFPSNLVSAAFRSYSTTYEERVKVPV
GQEVEGMNILGLVVFAIVFGVALRKLGPEGELLIRFFNSFNEATMVLVSW
IMWYAPVGIMFLVAGKIVEMEDVGLLFARLGKYILCCLLGHAIHGLLVLP
LIYFLFTRKNPYRFLWGIVTPLATAFGTSSSSATLPLMMKCVEENNGVAK
HISRFILPIGATVNMDGAALFQCVAAVFIAQLSQQSLDFVKIITILVTAT
ASSVGAAGIPAGGVLTLAIILEAVNLPVDHISLILAVDWLVDRSCTVLNV
EGDALGAGLLQNYVD
3D structure
PDB8qrs Structural basis of the obligatory exchange mode of human neutral amino acid transporter ASCT2.
ChainB
Resolution2.86 Å
3D
structure
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Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 GLN B S353 M387 A390 G430 I431 G435 D464 C467 T468 N471 S281 M315 A318 G358 I359 G363 D392 C395 T396 N399
External links
PDB RCSB:8qrs, PDBe:8qrs, PDBj:8qrs
PDBsum8qrs
PubMed39095408
UniProtQ15758|AAAT_HUMAN Neutral amino acid transporter B(0) (Gene Name=SLC1A5)

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