Structure of PDB 8qrr Chain B

Receptor sequence
>8qrrB (length=420) Species: 9606 (Homo sapiens) [Search protein sequence]
CLRANLLVLLTVVAVVAGVALGLGVSGAGGALALGPERLSAFVFPGELLL
RLLRMIILPLVVCSLIGGAASLDPGALGRLGAWALLFFLVTTLLASALGV
GLALALQPGAASAASKEVLDSFLDLARNIFPSNLVSAAFRSYSTTYEERR
VKVPVGQEVEGMNILGLVVFAIVFGVALRKLGPEGELLIRFFNSFNEATM
VLVSWIMWYAPVGIMFLVAGKIVEMEDVGLLFARLGKYILCCLLGHAIHG
LLVLPLIYFLFTRKNPYRFLWGIVTPLATAFGTSSSSATLPLMMKCVEEN
NGVAKHISRFILPIGATVNMDGAALFQCVAAVFIAQLSQQSLDFVKIITI
LVTATASSVGAAGIPAGGVLTLAIILEAVNLPVDHISLILAVDWLVDRSC
TVLNVEGDALGAGLLQNYVD
3D structure
PDB8qrr Structural basis of the obligatory exchange mode of human neutral amino acid transporter ASCT2.
ChainB
Resolution2.78 Å
3D
structure
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Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 GLN B S352 S353 A390 G430 I431 D464 T468 N471 S285 S286 A323 G363 I364 D397 T401 N404
External links
PDB RCSB:8qrr, PDBe:8qrr, PDBj:8qrr
PDBsum8qrr
PubMed39095408
UniProtQ15758|AAAT_HUMAN Neutral amino acid transporter B(0) (Gene Name=SLC1A5)

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