Structure of PDB 8qro Chain B

Receptor sequence
>8qroB (length=414) Species: 9606 (Homo sapiens) [Search protein sequence]
LRANLLVLLTVVAVVAGVALGLGVSGAGGALALGPERLSAFVFPGELLLR
LLRMIILPLVVCSLIGGAASLDPGALGRLGAWALLFFLVTTLLASALGVG
LALALQPGASKEVLDSFLDLARNIFPSNLVSAAFRSYSTTYEERVKVPVG
QEVEGMNILGLVVFAIVFGVALRKLGPEGELLIRFFNSFNEATMVLVSWI
MWYAPVGIMFLVAGKIVEMEDVGLLFARLGKYILCCLLGHAIHGLLVLPL
IYFLFTRKNPYRFLWGIVTPLATAFGTSSSSATLPLMMKCVEENNGVAKH
ISRFILPIGATVNMDGAALFQCVAAVFIAQLSQQSLDFVKIITILVTATA
SSVGAAGIPAGGVLTLAIILEAVNLPVDHISLILAVDWLVDRSCTVLNVE
GDALGAGLLQNYVD
3D structure
PDB8qro Structural basis of the obligatory exchange mode of human neutral amino acid transporter ASCT2.
ChainB
Resolution2.6 Å
3D
structure
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Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 GLN B S352 S353 A390 G430 I431 D464 C467 T468 N471 S279 S280 A317 G357 I358 D391 C394 T395 N398
External links
PDB RCSB:8qro, PDBe:8qro, PDBj:8qro
PDBsum8qro
PubMed39095408
UniProtQ15758|AAAT_HUMAN Neutral amino acid transporter B(0) (Gene Name=SLC1A5)

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