Structure of PDB 8qno Chain B

Receptor sequence

>8qnoB (length=421) Species: 2261 (Pyrococcus furiosus) [Search protein sequence]

MDCGKDYCVKDLSLAEEGWKKIDWVSRFMPVLQYIKREFEEKKPFKGVRI
AATLHLEMKTAFLLLTLKAGGAEVSAAASNPLSTQDDVVAALAKAGVKVY
AIRGESREQYYEFMHKALDIRPNIIIDDGADMISLVHKERQEMLDEIWGG
SEETTTGVIRLRAMEKAGILKFPVIAVNDSYMKYLFDNRYGTGQSTWDGI
MRATNLLIAGKNVVVVGYGWCGRGIAMRARGLGATVIVVEVDPIKALEAR
MDGFLVMDMKEAAKIGDIFVTATGNIKCIRREHFELMKDGAIMANAGHFD
VEIWKPDLEKLAVEINNPRPNVTEYKLKDGRRLYLLADGRLVNLVAADGH
PAEIMDMSFALQAKAAEYIKDNHERLEPKVYILPREIDEMVARIKLESMG
IKIEELTEEQKKYLESWEHGT

3D structure

PDB

8qno Structure, function and substrate preferences of archaeal S-adenosyl-L-homocysteine hydrolases.

Chain

Resolution

2.033 Å

3D
structure

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Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	NOS	B	H55 E57 K59 D128 E153 T154 D187 H298 L341 L344 G349 H350 M355 F359	H55 E57 K59 D128 E153 T154 D187 H298 L341 L344 G349 H350 M355 F359
BS02	NAD	B	T154 T155 T156 N188 G217 G219 W220 C221 E240 V241 K245 A272 T273 G274 N275 C278 A296 H298 N343 H350	T154 T155 T156 N188 G217 G219 W220 C221 E240 V241 K245 A272 T273 G274 N275 C278 A296 H298 N343 H350

External links

PDB	RCSB:8qno, PDBe:8qno, PDBj:8qno
PDBsum	8qno
PubMed	38548921
UniProt	P50251\|SAHH_PYRFU Adenosylhomocysteinase (Gene Name=ahcY)

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