Structure of PDB 8qlr Chain B

Receptor sequence
>8qlrB (length=262) Species: 9606 (Homo sapiens) [Search protein sequence]
TNLKADPEELFTKLEKIGKGSFGEVFKGIDNRTQKVVAIKIIDLEEAEDE
IEDIQQEITVLSQCDSPYVTKYYGSYLKDTKLWIIMEYLGGGSALDLLEP
GPLDETQIATILREILKGLDYLHSEKKIHRDIKAANVLLSEHGEVKLADF
GVATPFWMAPEVIKQYDSKADIWSLGITAIELARGEPPHSELHPMKVLFL
IPKNNPPTLEGNYSKPLKEFVEACLNKEPSFRPTAKELLKHKFILRNAKK
TSYLTELIDAHH
3D structure
PDB8qlr Human MST3 (STK24) kinase in complex with inhibitor MR24
ChainB
Resolution1.85 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.11.1: non-specific serine/threonine protein kinase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 VYN B F47 V50 A63 K65 E82 I83 L86 I109 M111 L114 G117 A160 L163 D174 F22 V25 A38 K40 E57 I58 L61 I84 M86 L89 G92 A135 L138 D149
Gene Ontology
Molecular Function
GO:0004672 protein kinase activity
GO:0005524 ATP binding
Biological Process
GO:0006468 protein phosphorylation

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Molecular Function
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Biological Process
External links
PDB RCSB:8qlr, PDBe:8qlr, PDBj:8qlr
PDBsum8qlr
PubMed38422480
UniProtQ9Y6E0|STK24_HUMAN Serine/threonine-protein kinase 24 (Gene Name=STK24)

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