Structure of PDB 8qer Chain B

Receptor sequence
>8qerB (length=413) Species: 287 (Pseudomonas aeruginosa) [Search protein sequence]
MSRRRVVITGMGMLSPLGLDVPSSWEGILAGRSGIAPIEHMDLSAYSTRF
GGSVKGFNVEEYLSAKEARKLDLFIQYGLAASFQAVRDSGLEVTDANRER
IGVSMGSGIGGLTNIENNCRSLFEQGPRRISPFFVPGSIINMVSGFLSIH
LGLQGPNYALTTAATTGTHSIGMAARNIAYGEADVMVAGGSEMAACGLGL
GGFGAARALSTRNDEPTRASRPWDRDRDGFVLSDGSGALVLEELEHARAR
GARIYAELVGFGMSGDAFHMTAPPEDGAGAARCMKNALRDAGLDPRQVDY
INAHGTSTPAGDIAEIAAVKSVFGEHAHALSMSSTKSMTGHLLGAAGAVE
AIFSVLALRDQVAPPTINLDNPDEGCDLDLVAHEAKPRKIDVALSNSFGF
GGTNGTLVFRRFA
3D structure
PDB8qer New starting points for antibiotics targeting P. aeruginosa FabF discovered by crystallographic fragment screening followed by hit expansion
ChainB
Resolution1.95 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.3.1.179: beta-ketoacyl-[acyl-carrier-protein] synthase II.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 UGL B T271 P273 H304 G311 H341 F398 G399 F400 T271 P273 H304 G311 H341 F398 G399 F400
Gene Ontology
Molecular Function
GO:0004315 3-oxoacyl-[acyl-carrier-protein] synthase activity
GO:0016746 acyltransferase activity
GO:0016747 acyltransferase activity, transferring groups other than amino-acyl groups
GO:0046872 metal ion binding
Biological Process
GO:0006633 fatty acid biosynthetic process
Cellular Component
GO:0005829 cytosol

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8qer, PDBe:8qer, PDBj:8qer
PDBsum8qer
PubMed
UniProtG3XDA2

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