Structure of PDB 8qaw Chain B

Receptor sequence
>8qawB (length=185) Species: 3880 (Medicago truncatula) [Search protein sequence]
GARIGEMKRVTKETNVSVKINLDGTGVADNSSGIPFLDHMLDQLASHGLF
DVHVKATGDTHIDDHHTNEDVALAIGTALLQALGDRKGINRFGNFSAPLD
EALVHVSLDLSGRPHLGYDLNIPTQRVGKYDTQLVEHFFQSLVNTSGMTL
HIRQFSGTNSHHIIEATFKAFARALRQATEYDTRR
3D structure
PDB8qaw Targeting imidazole-glycerol phosphate dehydratase in plants: novel approach for structural and functional studies, and inhibitor blueprinting.
ChainB
Resolution1.55 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 4.2.1.19: imidazoleglycerol-phosphate dehydratase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 IMD B E89 H142 E145 D146 E13 H66 E69 D70
BS02 MN B H141 E145 H213 H65 E69 H137
BS03 MN B H115 H237 E241 H39 H161 E165
Gene Ontology
Molecular Function
GO:0004424 imidazoleglycerol-phosphate dehydratase activity
Biological Process
GO:0000105 L-histidine biosynthetic process

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Molecular Function
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Biological Process
External links
PDB RCSB:8qaw, PDBe:8qaw, PDBj:8qaw
PDBsum8qaw
PubMed38559763
UniProtA0A072VQG6

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