Structure of PDB 8q41 Chain B

Receptor sequence
>8q41B (length=419) Species: 509193 (Thermoanaerobacter brockii subsp. finnii Ako-1) [Search protein sequence]
EKVLVLIVGTNPLPNYVVGSHLKEKYDKFVLIYSEKNDKINQNSTYDYAK
KLKEHLNLNDKCIFLPLSDVSNSEKIINDLREKFPSEDFVEVHLNYTGGT
KTMVVHIYNFLKEKFEGSYLDARDYKLVYDAISLKDTIKIDINTLLSIHL
YEDIHFEFYDTYSYKQKFVDSFDKISQEIEKAIKDDKGEDFVKWLEDPFR
KIFKGENKLLEKTAKFKKHIEKLLSPIVKFNEKTPQFIWDILNAFPEGKK
LNDGQKLWIPDDKITNDNLSSRVKDTVEFLNGKWFEWYVYSQIKSELLDR
KLKEGEHFGISLKAQKKDSPYFALDIFLINGYQLIGISLTTSSTRELCKL
KGFEVIHRVRQIGGDESKAILITGMDKSKTEDLQKDLAYETGSTQKRFVV
FGIDDWADIGSKICEEVFK
3D structure
PDB8q41 Substrate selectivity and catalytic activation of the type III CRISPR-associated ancillary nuclease Can2
ChainB
Resolution2.38 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna B R213 K217 K301 P338 Y339 T358 T359 L365 R200 K204 K283 P320 Y321 T340 T341 L347
BS02 rna B G11 T12 P16 S36 T47 T99 G101 T102 K103 Y128 A131 R132 E384 G410 G9 T10 P14 S34 T45 T97 G99 T100 K101 Y119 A122 R123 E366 G392
BS03 MN B D343 L357 D325 L339
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
GO:0046872 metal ion binding

View graph for
Molecular Function
External links
PDB RCSB:8q41, PDBe:8q41, PDBj:8q41
PDBsum8q41
PubMed38033326
UniProtE8URK0

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