Structure of PDB 8q3a Chain B

Receptor sequence
>8q3aB (length=164) Species: 9606 (Homo sapiens) [Search protein sequence]
GTSKLKYVLQDARFFLIKSNNHENVSLAKAKGVWSTLPVNEKKLNLAFRS
ARSVILIFSVRESGKFQGFARLSSESHHGGSPIHWVLPAGMSAKMLGGVF
KIDWICRRELPFTKSAHLTNPWNEHKPVKIGRDGQEIELECGTQLCLLFP
PDESIDLYQVIHKM
3D structure
PDB8q3a Crystal structure of YTHDC1 in complex with Compound 22 (ZA_393)
ChainB
Resolution1.43 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 IYQ B K361 S362 N363 N364 N367 W377 S378 L380 W428 P431 M434 D476 K18 S19 N20 N21 N24 W34 S35 L37 W85 P88 M91 D133
Gene Ontology

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Molecular Function
External links
PDB RCSB:8q3a, PDBe:8q3a, PDBj:8q3a
PDBsum8q3a
PubMed38787793
UniProtQ96MU7|YTDC1_HUMAN YTH domain-containing protein 1 (Gene Name=YTHDC1)

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