Structure of PDB 8q35 Chain B

Receptor sequence
>8q35B (length=164) Species: 9606 (Homo sapiens) [Search protein sequence]
GTSKLKYVLQDARFFLIKSNNHENVSLAKAKGVWSTLPVNEKKLNLAFRS
ARSVILIFSVRESGKFQGFARLSSESHHGGSPIHWVLPAGMSAKMLGGVF
KIDWICRRELPFTKSAHLTNPWNEHKPVKIGRDGQEIELECGTQLCLLFP
PDESIDLYQVIHKM
3D structure
PDB8q35 Crystal structure of YTHDC1 in complex with Compound 16 (ZA_354)
ChainB
Resolution1.31 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 IWM B K361 S362 N363 N364 N367 W377 S378 R404 W428 P431 D476 K18 S19 N20 N21 N24 W34 S35 R61 W85 P88 D133
Gene Ontology

View graph for
Molecular Function
External links
PDB RCSB:8q35, PDBe:8q35, PDBj:8q35
PDBsum8q35
PubMed38787793
UniProtQ96MU7|YTDC1_HUMAN YTH domain-containing protein 1 (Gene Name=YTHDC1)

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