Structure of PDB 8q33 Chain B

Receptor sequence
>8q33B (length=164) Species: 9606 (Homo sapiens) [Search protein sequence]
GTSKLKYVLQDARFFLIKSNNHENVSLAKAKGVWSTLPVNEKKLNLAFRS
ARSVILIFSVRESGKFQGFARLSSESHHGGSPIHWVLPAGMSAKMLGGVF
KIDWICRRELPFTKSAHLTNPWNEHKPVKIGRDGQEIELECGTQLCLLFP
PDESIDLYQVIHKM
3D structure
PDB8q33 Crystal structure of YTHDC1 in complex with Compound 15 (ZA_343)
ChainB
Resolution1.43 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 IWV B K361 S362 N363 N364 N367 W377 S378 L380 W428 R475 D476 K18 S19 N20 N21 N24 W34 S35 L37 W85 R132 D133
Gene Ontology

View graph for
Molecular Function
External links
PDB RCSB:8q33, PDBe:8q33, PDBj:8q33
PDBsum8q33
PubMed38787793
UniProtQ96MU7|YTDC1_HUMAN YTH domain-containing protein 1 (Gene Name=YTHDC1)

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