Structure of PDB 8q2y Chain B

Receptor sequence
>8q2yB (length=164) Species: 9606 (Homo sapiens) [Search protein sequence]
GTSKLKYVLQDARFFLIKSNNHENVSLAKAKGVWSTLPVNEKKLNLAFRS
ARSVILIFSVRESGKFQGFARLSSESHHGGSPIHWVLPAGMSAKMLGGVF
KIDWICRRELPFTKSAHLTNPWNEHKPVKIGRDGQEIELECGTQLCLLFP
PDESIDLYQVIHKM
3D structure
PDB8q2y Crystal structure of YTHDC1 in complex with Compound 11 (ZA_572)
ChainB
Resolution1.71 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 IVI B K361 S362 N363 N364 N367 W377 S378 W428 D476 K18 S19 N20 N21 N24 W34 S35 W85 D133
Gene Ontology

View graph for
Molecular Function
External links
PDB RCSB:8q2y, PDBe:8q2y, PDBj:8q2y
PDBsum8q2y
PubMed38787793
UniProtQ96MU7|YTDC1_HUMAN YTH domain-containing protein 1 (Gene Name=YTHDC1)

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