Structure of PDB 8q2t Chain B

Receptor sequence
>8q2tB (length=162) Species: 9606 (Homo sapiens) [Search protein sequence]
GTSKLKYVLQDARFFLIKSNNHENVSLAKAKGVWSTLPVNEKKLNLAFRS
ARSVILIFSVRESGKFQGFARLSSESHHGGSPIHWVLPMSAKMLGGVFKI
DWICRRELPFTKSAHLTNPWNEHKPVKIGRDGQEIELECGTQLCLLFPPD
ESIDLYQVIHKM
3D structure
PDB8q2t Crystal structure of YTHDC1 in complex with Compound 5 (ZA_236)
ChainB
Resolution1.41 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 IUA B K361 S362 N363 N364 N367 W377 S378 W428 P431 M434 D476 K18 S19 N20 N21 N24 W34 S35 W85 P88 M89 D131
Gene Ontology

View graph for
Molecular Function
External links
PDB RCSB:8q2t, PDBe:8q2t, PDBj:8q2t
PDBsum8q2t
PubMed38787793
UniProtQ96MU7|YTDC1_HUMAN YTH domain-containing protein 1 (Gene Name=YTHDC1)

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