Structure of PDB 8q23 Chain B

Receptor sequence

>8q23B (length=394) Species: 9606 (Homo sapiens) [Search protein sequence]

QGPAKTMEEASKRSYQFWDTQPVPKLGEVVNTHGPVEPDKDNIRQEPYTL
PQGFTWDALDLGDRGVLKELYTLLNENYVEDDDNMFRFDYSPEFLLWALR
PPGWLPQWHCGVRVVSSRKLVGFISAIPANIHIYDTEKKMVEINFLCVHK
KLRSKRVAPVLIREITRRVHLEGIFQAVYTAGVVLPKPVGTCRYWHRSLN
PRKLIEVKFSHLSRNMTMQRTMKLYRLPETPKTAGLRPMETKDIPVVHQL
LTRYLKQFHLTPVMSQEEVEHWFYPQENIIDTFVVENANGEVTDFLSFYT
LPSTIMNHPTHKSLKAAYSFYNVHTQTPLLDLMSDALVLAKMKGFDVFNA
LDLMENKTFLEKLKFGIGDGNLQYYLYNWKCPSMGAEKVGLVLQ

3D structure

PDB

8q23 HsNMT1 in complex with both MyrCoA and Ac-D-ORN-SFSKPR inhibitor peptide

Chain

Resolution

1.9 Å

3D
structure

[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	peptide	B	D183 D185 F188 F190 N246 T282 Y296 H298 F311 S405 I469 G470 D471 G472 N473	D81 D83 F86 F88 N144 T180 Y194 H196 F209 S303 I367 G368 D369 G370 N371
BS02	MYA	B	Y117 Q118 F119 W120 Y180 V181 I245 L248 C249 V250 R255 S256 R258 A260 P261 T268 V271 A279 Y281 T282 L287 Y479	Y15 Q16 F17 W18 Y78 V79 I143 L146 C147 V148 R153 S154 R156 A158 P159 T166 V169 A177 Y179 T180 L185 Y377

External links

PDB	RCSB:8q23, PDBe:8q23, PDBj:8q23
PDBsum	8q23
PubMed
UniProt	P30419\|NMT1_HUMAN Glycylpeptide N-tetradecanoyltransferase 1 (Gene Name=NMT1)

[Back to BioLiP]