Structure of PDB 8put Chain B

Receptor sequence
>8putB (length=312) Species: 43080 (Sulfolobus islandicus) [Search protein sequence]
MINREDLLKNPVEDIALRDLEKYSDIVNVFDKIYGFSSEGIVRGSKILKE
MIKDADLRFLSFTANLVSTGLRGLFADLVKRGYFNIIVTTGGTIDHDLAR
SFGGVYYKGSFDIDDAMLKDLEIHRLGNVLVPFESYGKVIEEIVRKFLPE
IAKDKKEIPAYELLWEFGKRISDSNSILRAAYEKKVPVIVPGIVDGSFGT
NLFIQSQFLNFKINLFEDMRLIKDLVFSCKKSGALIIGGGISKHHTIWWN
QFKDGLDYAVYVTTAQEYDGSLSGAKPREAISWNKIRPNAKHATIYGDAT
IIVPILAASLLS
3D structure
PDB8put Crystal structure of archaeal IF5A-DHS complex reveals insights into the hypusination mechanism.
ChainB
Resolution2.0 Å
3D
structure
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Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 NAD B G240 H244 D269 S271 L272 S273 G240 H244 D269 S271 L272 S273
BS02 NAD B T63 A64 N65 T90 G91 G92 L126 D195 G238 G239 T263 T264 A265 A299 T63 A64 N65 T90 G91 G92 L126 D195 G238 G239 T263 T264 A265 A299
Gene Ontology
Molecular Function
GO:0016740 transferase activity
GO:0034038 deoxyhypusine synthase activity
Biological Process
GO:0008612 peptidyl-lysine modification to peptidyl-hypusine
Cellular Component
GO:0005737 cytoplasm

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8put, PDBe:8put, PDBj:8put
PDBsum8put
PubMed38582076
UniProtC4KGY0|DHYS_SULIK Probable deoxyhypusine synthase (Gene Name=dys)

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