Structure of PDB 8puq Chain B

Receptor sequence

>8puqB (length=146) Species: 9796 (Equus caballus)

VQLSGEEKAAVLALWDKVNEEEVGGEALGRLLVVYPWTQRFFDSFGDLSN
PGAVMGNPKVKAHGKKVLHSFGEGVHHLDNLKGTFAALSELHCDKLHVDP
ENFRLLGNVLVVVLARHFGKDFTPELQASYQKVVAGVANALAHKYH

3D structure

• PDB: 8puq Anaerobic fixed-target serial crystallography using sandwiched silicon nitride membranes
• Chain: B
• Resolution: 1.95 Å

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	HEM	B	F41 F42 H63 S70 F71 H92 L96 N102 F103 L141	F41 F42 H63 S70 F71 H92 L96 N102 F103 L141

Gene Ontology

Molecular Function

• GO:0004601 peroxidase activity
• GO:0005344 oxygen carrier activity
• GO:0019825 oxygen binding
• GO:0020037 heme binding
• GO:0031720 haptoglobin binding
• GO:0031721 hemoglobin alpha binding
• GO:0043177 organic acid binding
• GO:0046872 metal ion binding

Biological Process

• GO:0015671 oxygen transport
• GO:0042744 hydrogen peroxide catabolic process
• GO:0098869 cellular oxidant detoxification

Cellular Component

• GO:0005833 hemoglobin complex
• GO:0031838 haptoglobin-hemoglobin complex

External links

• PDB: RCSB:8puq, PDBe:8puq, PDBj:8puq
• PDBsum: 8puq
• PubMed: 37860963
• UniProt: P02062|HBB_HORSE Hemoglobin subunit beta (Gene Name=HBB)