Structure of PDB 8pq5 Chain B

Receptor sequence

>8pq5B (length=372) Species: 9606 (Homo sapiens) [Search protein sequence]

MYIKQVIIQGFRSYRDQTIVDPFSSKHNVIVGRNGSGKSNFFYAIQFVLS
DEFSHLRPEQRLALLHEGTGPRVISAFVEIIFDNSDNRLPIDKEEVSLRR
VIGAKKDQYFLDKKMVTKNDVMNLLESAGFSRSNPYYIVKQGKINQMATA
PDSQRLKLLREVAGTRVYDERKEESISLMKETEGKREKINELLEELDRGY
KSIMELMNVLELRKYEAIQLTFKQVSKNFSEVFQKLVPGGKATLVMKFTG
VGIRVSFTGKQGEMREMQQLSGGQKSLVALALIFAIQKCDPAPFYLFDQI
DQALDAQHRKAVSDMIMELAVHAQFITTTFRPELLESADKFYGVKFRNKV
SHIDVITAEMAKDFVEDDTTHG

3D structure

PDB

8pq5 Conformational dynamics of the human Cohesin ATPase module

Chain

Resolution

4.4 Å

3D
structure

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Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	ATP	B	R1110 Q1114 L1115 S1116 G1117 G1118	R265 Q269 L270 S271 G272 G273
BS02	ATP	B	R12 R33 N34 G35 S36 G37 K38 S39 N40 F1175	R12 R33 N34 G35 S36 G37 K38 S39 N40 F330

External links

PDB	RCSB:8pq5, PDBe:8pq5, PDBj:8pq5
PDBsum	8pq5
PubMed

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