Structure of PDB 8pos Chain B

Receptor sequence
>8posB (length=165) Species: 292805 (Wolbachia endosymbiont strain TRS of Brugia malayi) [Search protein sequence]
EGVTIEFKIVGLNKKLKVFTTCPHTLFGASFCAVAIEHPIVQDLMSKEIQ
DLISSIKIQGEKVGIYTGLNVKHPFLDKELPLYVANFVLMEYREGAIFGC
PAHDQRDFEFAQEYDLPIIPVISSEEYTNNSIMFNSEFLNGLTVSEARKV
IVEKLEEKGIGKKTI
3D structure
PDB8pos Targeting A Microbiota Wolbachian Aminoacyl-tRNA Synthetase To Block Its Pathogenic Host
ChainB
Resolution2.137 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 6.1.1.4: leucine--tRNA ligase.
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 7RZ B F240 T241 T242 C243 T246 L313 Y316 I321 F322 D328 R330 D331 F19 T20 T21 C22 T25 L89 Y92 I97 F98 D104 R106 D107
External links
PDB RCSB:8pos, PDBe:8pos, PDBj:8pos
PDBsum8pos
PubMed38985862
UniProtQ5GS31|SYL_WOLTR Leucine--tRNA ligase (Gene Name=leuS)

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