Structure of PDB 8pj1 Chain B

Receptor sequence

>8pj1B (length=142) Species: 9606 (Homo sapiens)

DIQTERAYQKQPTIFQNKKKEKLPRYYKNIGLGFKTPKEAIEGTYIDKKC
PFTGNVSIRGRILSGVVTKMKMQRTIVIRRDYLHYIRKYNRFEKRHKNMS
VHLSPCFRDVQIGDIVTVGECRPLSKTVRFNVLKVTKAAGTK

3D structure

• PDB: 8pj1 Structural basis for translational control by the human 48S initiation complex from codon scanning toward subunit joining
• Chain: B
• Resolution: 3.4 Å

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	rna	B	R8 Q11 F17 Y36 N39 I40 G41 L42 K58 K59 N65 S67 I68 R69 R71 L73 K79 K81 M82 Q83 T85 R89 R90 Y92 R97 K98 Y99 K104 R105 H106 K107 N108 E130 R132 P133 L134 S135 K136 T137 R139 F140 K152	R6 Q9 F15 Y26 N29 I30 G31 L32 K48 K49 N55 S57 I58 R59 R61 L63 K69 K71 M72 Q73 T75 R79 R80 Y82 R87 K88 Y89 K94 R95 H96 K97 N98 E120 R122 P123 L124 S125 K126 T127 R129 F130 K142

External links

• PDB: RCSB:8pj1, PDBe:8pj1, PDBj:8pj1
• PDBsum: 8pj1
• UniProt: P62280|RS11_HUMAN Small ribosomal subunit protein uS17 (Gene Name=RPS11)