Structure of PDB 8p5i Chain B

Receptor sequence
>8p5iB (length=273) Species: 9606 (Homo sapiens) [Search protein sequence]
TETVGKFEFSRKDLIGHGAFAVVFKGRHREKHDLEVAVKCINKKNLAKSQ
TLLGKEIKILKELKHENIVALYDFQEMANSVYLVMEYCNGGDLADYLHAM
RTLSEDTIRLFLQQIAGAMRLLHSKGIIHRDLKPQNILLSNPAGRRANPN
SIRVKIADFGFARYLQSNMMAATLCGSPMYMAPEVIMSQHYDGKADLWSI
GTIVYQCLTGKAPFQASSPQDLRLFYEKNKTLVPTIPAATSAPLRQLLLA
LLQRNHKDRMDFDEFFHHPFLDA
3D structure
PDB8p5i Crystal structures of ULK1 in complex with KCGS compounds
ChainB
Resolution1.829 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number 2.7.11.1: non-specific serine/threonine protein kinase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 WYX B M92 Y94 C95 G98 D99 L145 D165 M85 Y87 C88 G91 D92 L138 D158
BS02 MG B E191 Y198 D199 H263 E184 Y191 D192 H256
BS03 MG B H136 D165 F166 F168 H129 D158 F159 F161
External links
PDB RCSB:8p5i, PDBe:8p5i, PDBj:8p5i
PDBsum8p5i
PubMed
UniProtO75385|ULK1_HUMAN Serine/threonine-protein kinase ULK1 (Gene Name=ULK1)

[Back to BioLiP]