Structure of PDB 8p0u Chain B

Receptor sequence
>8p0uB (length=587) Species: 11569 (Thogotovirus thogotoense) [Search protein sequence]
MNLFTPRSEINPTTTQELLYAYTGPAPVAYGTRTRAVLENIIRPYQYFYK
EPNVQRALDIKTGCKEPEDINVEGPSSGFHTASVLKLADNFFRKYRPAME
KLKYWILVKLPKLKYAELSKGRQTYSFIHKRNLPAPIALEETVEFLEQNL
RRKIGPTLLSYCQAIADVMELDETTYEGATYTIKFSREELWDQMRTLNTM
WKHLERGRLNRRTIATPSMLIRGFVKIVEDAAKEILENVPTSGVPVGGEE
KLAKLASKQTFHTAVTGELSGDQEKFNECLDPDAMRLMWTVFLRKLGCPD
WIMELFNIPFMVFKSKLADMGEGLVYTKGKLTDRKPLGEMPSEFDDLVRN
VVGNSISCRLGMFMGMYNLTSTLLALISIEREELTGSHVESSDDFIHFFN
CKTHEEMFKQAETLRLTLKLVGINMSPSKCILISPAGIGEFNSKFHHRDF
VGNVATELPALVPNGTNPMTDLAMGLNVIKHSVNTGQMNLCTGALAMRIF
NHAYKYAYMALGVTRRTRFMEENAITPLLTNQGASPVHSFSTMHLDEVAL
RRHLGLLDEETLRRILNPNNPVTDYSVPSCFKYTLSR
3D structure
PDB8p0u Thogoto virus polymerase
ChainB
Resolution2.92 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.7.48: RNA-directed RNA polymerase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 rna B Y535 L540 G541 V542 Y506 L511 G512 V513
BS02 rna B Y30 G31 T32 R35 R363 Y30 G31 T32 R35 R334
BS03 MG B G300 D301 D423 E469 G271 D272 D394 E440
Gene Ontology
Molecular Function
GO:0000166 nucleotide binding
GO:0003968 RNA-dependent RNA polymerase activity
GO:0034062 5'-3' RNA polymerase activity
Biological Process
GO:0001172 RNA-templated transcription

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Molecular Function
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Biological Process
External links
PDB RCSB:8p0u, PDBe:8p0u, PDBj:8p0u
PDBsum8p0u
PubMed
UniProtO41353|RDRP_THOGV RNA-directed RNA polymerase catalytic subunit (Gene Name=Segment)

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