Structure of PDB 8p0a Chain B

Receptor sequence

>8p0aB (length=314) Species: 9606 (Homo sapiens) [Search protein sequence]

MYIKQVIIQGFRSYRDQTIVDPFSSKHNVIVGRNGSGKSNFFYAIQFVLS
DEFSHLRPEQRLALLHEGTGPRVISAFVEIIFDNSDNRLPIDKEEVSLRR
VIGAKKDQYFLDKKMVTKNDVMNLLESAGFSRSNPYYIVKQGKINQMATA
PDSQRLKLLREVIQLTFKQVSKNFSEVFQKLVPGGKATLVMKTGVGIRVS
FTGKQGEMREMQQLSGGQKSLVALALIFAIQKCDPAPFYLFDQIDQALDA
QHRKAVSDMIMELAVHAQFITTTFRPELLESADKFYGVKFRNKVSHIDVI
TAEMAKDFVEDDTT

3D structure

PDB

8p0a Human Cohesin ATPase module

Chain

Resolution

3.67 Å

3D
structure

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Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	ATP	B	F1102 R1110 Q1114 S1116 G1117 G1118	F201 R209 Q213 S215 G216 G217
BS02	ATP	B	R12 N34 G35 S36 G37 K38 S39 N40 A63 Q141 F1175	R12 N34 G35 S36 G37 K38 S39 N40 A63 Q141 F274

External links

PDB	RCSB:8p0a, PDBe:8p0a, PDBj:8p0a
PDBsum	8p0a
PubMed
UniProt	Q9UQE7\|SMC3_HUMAN Structural maintenance of chromosomes protein 3 (Gene Name=SMC3)

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